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SELECTED REFERENCES

For non-colorectal-specific tumour modelling articles, see general references.

de la Chapelle, A. (2004).
Genetic predisposition to colorectal cancer. Nature Reviews Cancer 4: 769 - 780.
Drasdo, D. and Loeffler, M. (2001).
Individual-based models to growth and folding in one-layered tissues: intestinal crypts and early development. Nonlinear Analysis 47: 245 - 256.
Fearon, E.R. and Vogelstein, B. (1990).
A genetic model for colorectal tumorigenesis. Cell 61: 759 - 767.
Fodde,R., Smits, R. and Clevers, H. (2001).
APC, signal transduction and genetic instability in colorectal cancer. Nature Reviews Cancer 1: 55 - 67.
Hanahan, D. and Weinberg, R.A. (2000).
The hallmarks of cancer. Cell 100: 57 - 70.
Ilyas, M. (2005).
Wnt signalling and the mechanistic basis of tumour development. Journal of Pathology 205: 130 - 144.
van Leeuwen, I.M.M., Byrne, H.M., Jensen, O.E. and King, J.R. (2006).
Crypt dynamics and colorectal cancer: advances in mathematical modelling. Cell Proliferation, in press.
Luebeck, E.G. and Moolgavkar, S.H. (2002).
Multistage carcinogenesis and the incidence of colorectal cancer. PNAS 99: 15095 - 15100.
Meineke, F.A., Potten, C.S. and Loeffler, M. (2001).
Cell migration and organization in the intestinal crypt using a lattice-free model. Cell Proliferation 34: 253 - 266.
Potten, C.S. and Loeffler, M. (1990).
Stem cells: attributes, spirals, pitfalls and uncertainties. Lessons for and from the crypt. Development 119: 1001 -1020.
Preston, S. L. et al. (2003).
Bottom-up histogenesis of colorectal adenomas: origin in the monocryptal adenoma and initial expansion by crypt fission. Cancer Research 63: 3819-3825.
Radtke, F. and Clevers, H. (2005).
Self-renewal and cancer in the gut: two sides of the coin. Science 307: 1904 - 1909.
Tomlison, I., Sasieni, P. and Bodmer, W. (2002).
How many mutations in a cancer? American Journal of Pathology 160: 755 - 757.
Wodarz, D. and Komarova, N.L. (2005).
Computational Biology of Cancer. Lecture Notes and Mathematical Modeling. World Scientific Publishing, New Jersey.
Yatabe, Y., Tavare, S. and Shibata, D. (2001).
Investigating stem cells in human colon by using methylation patterns. PNAS 98: 10839 - 10844.

Ingeborg M.M. van Leeuwen
i.m.m.vanleeuwenmaths.nottingham.

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