Publications
The project is producing a rapidly expanding list of publications.
Where copyright restrictions allow, these can be downloaded from this page. The format and size of each document is indicated alongside the title. To be able to read the PDF documents you will need the Adobe Acrobat Reader.
- Gavaghan, D., Lloyd, S., Boyd, D.R.S., Jeffreys, P.W., Simpson, A., MacRandal, D.F., Sastry, L., Kleese van Dam, K.
- Integrative Biology - exploiting e-Science to combat fatal diseases. e-Science All Hands Meeting, September 2004 (PDF 219kb)
- Lloyd, S., Gavaghan, D., Whiteley, J., Pitt-Francis, J., Slaymaker, M., Boyd, D.R.S., Mac Randal, D.F., Kleese van Dam, K., Sastry, L.
- Gathering Requirements for the Integrative Biology project. e-Science All Hands Meeting, September 2004 (PDF 85kb)
- Integrative Biology - an EPSRC case study (Word 23kb)
- Integrative Biology information leaflet (PDF 402kb)
- De Fabritiis, G., Delgado-Buscalioni, R., Coveney, P.V.
- Hybrid molecular dynamics: coupled atomistic and continuum descriptions on the Grid. Poster presented at the ISCB/ECCB 2004 conference (PDF 98kb)
- De Fabritiis, G., Delgado-Buscalioni, R., Coveney, P.V.
- Energy controlled insertion of polar molecules in dense fluids. J. Chem. Phys. 121, 12139, 2004 (PDF 234kb)
- Lloyd, S., Simpson, A., Sastry, L., Gavaghan, D., Boyd, D.R.S.
- Integrative Biology - exploiting e-Science to combat fatal diseases. ERCIM News, No 60, January 2005
- Hanlon, D., Sastry, L., Kleese van Dam, K.
- Integrative Biology at CCLRC. ERCIM News, No 60, January 2005
- Gavaghan, D., Simpson, A.C., Lloyd, S., Mac Randal, D.F., Boyd, D.R.S.
- Towards a Grid Infrastructure to Support Biological Research. Accepted for publication in Philosophical Transactions of the Royal Society Series A , August 2005
- Handley, J., Clayton, R., Wood, J., Holden, A.V., Brodlie, K.
- Interaction with Cardiac Virtual Tissues on the Grid: The gViz Library. Accepted for publication in Proceedings of FIMH'05, 2005
- De Fabritiis, G., Serrano, M., Espanol, P., Coveney, P.V.
- Efficient numerical integrators for stochastic models. Accepted for publication in Physica A, 2005
- Bishop, M.J., Rodriguez, B., Eason, J., Whiteley, J.P., Noble, J.A., Trayanova, N., Gavaghan, D.J.
- Direct optical mapping signal synthesis over a geometrically accurate ventricular model. To be published in Heart Rhythm, 2005
- Rodriguez, B., Li, L., Eason, J., Efimov, I.R., Trayanova, N.
- Role of ventricular anatomy in vulnerability to electric shocks. To be published in Heart Rhythm, 2005
- Pitt-Francis, J., Garny, A., Gavaghan, D.
- Enabling computer models of the heart for high-performance computers and the grid. Accepted for publication in Philosophical Transactions of the Royal Society Series B, 2005
- Delgado-Buscalioni, R., De Fabritiis,G., Coveney, P. V.
- Determination of the chemical potential using energy biased sampling (PDF 431Kb), J. Chem. Phys. 123, (2005).
- Coveney, P. V., De Fabritiis, G., Harvey, M., Pickles, S. and Porter, A.
- On steering coupled models (PDF 468Kb), UK e-science all hands meeting (2005).
- Aslanidi, O.V., Brodlie, K.W., Clayton, R.H., Handley, J.W., Holden, A.V., Wood, J.
- Remote visualization and computational steering of cardiac virtual tissues using gViz. e-Science All Hands Meeting, September 2005
- Sastry, L., Nagella, S.
- Visualization on the UK National Grid Service using GAPtk, a generic toolkit. e-Science All Hands Meeting, September 2005
- Jirotka, M., Gavaghan, D., Welsh, E., Lloyd, S.
- Organisational and technological challenges of large-scale multi-disciplinary scientific research. e-Science All Hands Meeting, September 2005
- Lloyd, S., Simpson, A., Boyd, D., Gavaghan, D., Sastry, L., Mac Randall, D., Hanlon, D., Handley, J., de Fabrittis, G., Mascord, M., Seunarine, C., Williams, G., Weeks, K., Nagella, S., Fowler, R.
- Integrative Biology – The Challenges of Developing a Collaborative Research Environment for Heart and Cancer Modelling. Special edition Life Science Grids Journal, 2006
- Sher, A., Hinch, R., Gavaghan, D.
- Local control models of Ca2+ in the diadic space: the role of Na+-Ca2+ exchanger. Poster at 50th Biophysical Society Annual Meeting, Salt Lake City, Utah, February 18-22, 2006
- Aslanidi, O.V., Brodlie, K.W., Clayton, R.H., Handley, J.W., Holden, A.V., Wood, J.
- Multivariate Visualization of Cardiac Virtual Tissue. Second Workshop on Scientific Data Mining, Integration & Visualization (SMDIV2), e-Science Institute, University of Edinburgh, 14-15th December 2005
- De Fabritiis, G., Delgado-Buscalioni, R., Coveney, P.V.
- Modelling the mesoscale with molecular specificity. Preprint, 2006
- Gaffney, E.
- Modelling chemotherapy scheduling. Seminar at Clinical Pharmacology, University of Oxford, 9 February 2006
- van Leeuwen, I.M.M.
- Multiscale Modelling of Colorectal Cancer. Seminar at Vrije Universiteit, Amsterdam, 7 December 2005
- van Leeuwen, I.M.M.
- Biochemical networks in colorectal cancer. CoMPLEX seminar, University College London, 29 March 2005
- van Leeuwen, I.M.M., Byrne, H.M., Jensen, O.E., King, J.R.
- Crypt dynamics and colorectal cancer: advances in mathematical modelling. Cell Proliferation, 39(3), 157-181
- van Leeuwen, I.M.M.
- Multiscale modelling of colorectal cancer. CMM Seminar, Nottingam,1 November 2005
- van Leeuwen, I.M.M.
- Integrative modelling of colorectal cancer. Seminar at European Conference on Mathematical and Theoretical Biology (ECMTB05), Dresden University of Technology, Germany, 18-22 July 2005
- van Leeuwen, I.M.M., Edwards, C.M., Byrne, H.M., Chapman, S.J., Jensen, O.E., Mirams, G., King, J.R., Maini, P.
- Towards multiscale modelling of colorectal cancer. Poster at 1st NCRI Cancer Conference, Birmingham, 2-5 October 2005
- Bishop, M., Rodríguez, B., Eason, J., Whiteley, J., Trayanova, N., Gavaghan, D.
- Synthesis of voltage-sensitive optical signals: Application to panoramic optical mapping. Biophys J, 90(8):2938-2945, 2006
- Rodríguez, B., Eason, J., Trayanova, N.
- Differences between left and right ventricular anatomy determine the types of reentrant circuits induced by an external electric shock. Prog Biophys Mol Bio 90(1-3):399-413, 2006
- Rodríguez, B., Li, L., Eason, J., Efimov, I.R., Trayanova, N.
- Differences between left and right ventricular chamber geometry affect cardiac vulnerability to electric shocks. Circ Res, 97(2): 168-175, 2005
- Maharaj, T., Rodríguez, B., Blake, R., Trayanova, N., Gavaghan, D.
- Role of transmural heterogeneities in cardiac vulnerability to electric shocks. Heart Rhythm 2006
- Rodríguez, B., Tice, B., Blake, R., Eason, J., Gavaghan, D., Trayanova, N.
- Vulnerability to electric shocks in regional ischemia. Heart Rhythm 2006
- Bishop, M.J., Rodríguez, B., Eason, J.C., Whiteley, J.P., Noble, J.A., Trayanova, N., Gavaghan, D.J.
- Direct optical mapping signal synthesis over a geometrically accurate ventricular model. Heart Rhythm, 2(5):S220, 2005
- Rodríguez, B., Trayanova, N., Gavaghan, D.
- Role of shock timing in cardiac vulnerability to electric shocks. APICE International Symposium on Critical Care Medicine, Trieste (Italy), November 2005
- Maharaj, T., Rodríguez, B., Blake, R., Trayanova, N., Gavaghan, D.
- Transmural heterogeneities in action potential duration increase the upper limit of vulnerability. XXVIII International Conference of the IEEE/EMBS, 2006
- Rodríguez, B., Tice, B., Blake, R., Gavaghan, D., Trayanova, N.
- Vulnerability to electric shocks in the regionally-ischemic ventricles. XXVIII International Conference of the IEEE/EMBS, 2006
- Bishop, M., Rodríguez, B., Trayanova, N., Gavaghan, D.
- Modulation of Shock-End Virtual Electrode Polarisation as a Direct Result of 3D Fluorescent Photon Scattering. XXVIII International Conference of the IEEE/EMBS, 2006
- Rodriguez, B., Trayanova, N., Noble, D.
- Modeling cardiac ischemia. Annals of the New York Academy of Sciences
- Sher, A., Noble, P., Gavaghan, D., Hinch, R., Noble, D.
- Local regulation of SR Ca2+ release via Na+/Ca2+ exchanger. Poster at Heart Rhythm 2006
- Bollensdorff, C., Garny, A., Kohl, P.
- Axial stretch of isolated guinea pig ventricular myocytes increases whole-cell IKATP. European Working Group on Cardiac Cellular Electrophysiology, 2005
- Bollensdorff, C., Garny, A., Kohl, P.
- ATP-sensitive potassium current increases during axial stretch in isolated guinea pig ventricular myocytes. Biophysical Society Meeting, 2006
- Bollensdorff, C., Garny, A., Kohl, P.
- Axial stretch of isolated guinea pig ventricular myocytes increases ATP-sensitive potassium current. Joint meeting of the German Society of Physiology and the Federation of European Physiological Societies, 2006
Other publications associated with the project are listed in the Heart and Cancer sections of the website.